Diversity of Antioxidants; they are all super heroes

posted by on September 28th, 2018

Is your Super Food your Super Hero?

More and more we are seeing individuals, marketers and supplement providers come back to the term “super-food” when discussing “Beauty from Within”, “Brain Food” and even “Down and Dirty Detox”.

What does super food mean? Since there is no official definition, let us agree it means a food with a remarkable health benefit, or one that works to support multiple tissues, or areas of health in the body.

Antioxidants sum this up perfectly

Like me, you probably want to believe that your super-foods can come from untainted whole foods.  You want to believe that YOUR balanced diet could provide such a prescription for optimal health.  Unfortunately, in both practice and ecology, that is a gambling hand.  Diet is only a piece of the puzzle.  When we consider optimal cellular health or optimization, we need to look beyond diet and consider lifestyle.

Quality food means quality cells

We can all agree your cells and their function are dependent on protein, fats, carbohydrates, water, and trace minerals, therefore quality food means quality cells. No one is arguing against the importance of diet, however, reality suggests your environment, your sleep and your exercise habits will generate a burden that diet alone cannot or will not overcome. As such, our cells may fail to completely overcome oxidative damage from our lifestyle or exposure to toxins (1).  With this continued barrage of free radicals our cells will finally allow progressive damage limiting their function, how they communicate and ultimately duplicate.  All of this means we may need to take an approach beyond diet and consider the role of nutrient support

Antioxidants to the rescue

Let us take a real life example. A 2014 study in JAMA Ophthalmology looked at ocular aging and visual condition in an otherwise healthy and nourished population.  Looking at ocular health is an ideal way to establish total free-radical stress because the lens of the eye is particularly sensitive to oxidative damage (2).  The lens of the eye is subject to significant oxidative stress from UV light, pollution and aging.  Free-radical damage is linked to the development of age related macular degeneration and decline of ocular function. An interesting component of the study was a look beyond uncontrollable factors such as age and environment and evaluated the benefit of offsetting external causes of disease with dietary intake based on diversity of antioxidant content in foods.  Additionally looking at other modifiable factors beyond diet such as  elimination of exposure to first or second hand smoking or regular pharmaceutical interventions like corticosteroids, both of which rapidly increase oxidative stress to the lens of the eye and lead to the formation of abnormal cellular adhesions called Advanced Glycation end Products or AGE’s.  (2)

How can you eliminate or reduce your risk? 

Diet should always be your first approach to well-being and healthy aging. In fact, food constituents and supplementation maximizing nutrients routinely found in research to optimize cellular health is a sound way to support the aging process and minimize the risk of age related or environmental cellular decline (3). Research offers a ranking of many foods based on their nutrient density and antioxidant capacity.  Total Antioxidant Capacity or TAC is the current way researchers look at the benefits of foods with high ORAC value.  TAC, like ORAC value helps the consumer and practitioner make food choices or recommendations because the value is based on total capacity vs. looking at one natural constituent or one constituents benefit alone.

Polyphenols, flavonoids, carotenoids, and essential amino acids repeatedly appear at the top of the ORAC list and subsequently with some of the highest TAC values listed for optimal cellular health. Research supports the capacity of these constituents to regulate and assist DNA repair, aid in vascular protection, affect healthy cellular signaling and more. (3-7)

Polyphenols, which are responsible for rich color or pigment in the skins of fruits and vegetables, are the powerhouses of the super-food category. It is no wonder high ORAC foods like cranberries, blueberries, pomegranate and elderberry are holding so much real-estate on the health food aisle. Current research and its positive findings make these “super foods” or juices a simple step toward improved circulation, immune function, and general well-being.(3-7)

When is it prudent to look to add to your healthy diet?

It is expected that we eat approximately 1g of polyphenols per day. (8) That is only true if you eat a diet based on the colors of the rainbow, which many do not making supplementation all the more important in certain populations without access to foods or resources. In addition, even if we have acceptable access to healthy food choices, we need to be the educated consumer.  Processing methods such as sterilization, heating and even wrapping in plastic can be damaging to polyphenols.

By and large when we ask the question, “what is meaningful to my longevity?” The answer should be consuming foods or utilizing concentrated sources of high ORAC superfoods through supplementation is not just prudent, it is necessary.

Super food = Super Diversity = Super Antioxidant Capacity


1-Voeikov V: Reactive oxygen species: pathogens or sources of vital energy?, Journal of Alternative & Complementary Medicine 12(2):111-118, Mar 2006.

2- Rautiainen S, Lindblad BE, Morgenstern R, Wolk A. Total Antioxidant Capacity of the Diet and Risk of Age-Related CataractA Population-Based Prospective Cohort of Women. JAMA Ophthalmol. 2014;132(3):247–252. doi:10.1001/jamaophthalmol.2013.6241

3-Nijveldt R et al: Flavonoids: a review of probably mechanisms of action and potential applications, Am J Clin Nutr 74:418-25, 2001.

4- Shamitko N and Halpner A: Emerging new ingredients for cardiovascular health, poly methoxylated flavonoes, plant sterols and pomegranate, NutriNEWS Douglas labs, 2005.

5- Diebolt M et al: Polyphenols modulate calcium-independent mechanisms in human arterial tissue-engineered vascular media, J Vasc Surg Oct:46(4):764-72, 2007.

6- Tang FY et al: Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells, Nitric Oxide Jun:16(4):442-7, 2007.

7- Kumar S et al: Isoliquiritigenin inhibits IkappaBkinase activity and ROS generation to block TNF-alpha induced expression of cell adhesion molecules on human endothelial cells, Biochem Pharma May 15:73(10):1602-12, 2007.

8- Katz D et al: The effect of diet on endothelial function, Cardiol Rev Mar-Apr;15(2):62-6, 2007.